1. Pavicic, T., Calcium hydoxylapatite filler: an overview of safety and tolerability, J Drugs Dermatol, 12: 996-1002, 2013
2. Sadick, et.al., A multi-center, 47-month study of safety and efficacy of calcium hyroxylapatite for soft tissue augmentation of nasolabial folds and other areas of the face, Dermatol Surg, 33: S122-126 Suppl 2, 2007
3. Moers-Carpi, et. al, A multi-center randomized trial comparing calcium hydroxylapatite to two hyaluronic acids for treatment of nasolabial folds, Dermatol Surg, 33: S144-151 Suppl 2, 2007
4. Elmer, Aesthetic applications of calcium hydroxylapatite volumizing filler: an evidenced based review and discussion of current concepts, J Drugs Dermatolo, 12: 1345-54, 2013
5. Fakhre et. al., An evaluation of calcium hydroxylapatite (Radiesse) for cosmetic nasolabial fold correction: a meta-analysis and patient centric outcomes study, Ann Plast Surg, 63: 486-489, 2009,
6. Hevia, O. A Retrospective Review of Calcium Hydroxylapatite for Correction of Volume Loss in the Infraorbital Region, Dermatol Surg 2009;35:1487–1494
7. Bass LS, Smith S, Busso M, McClaren M. Calcium hydroxylate (Radiesse) for treatment of nasolabial folds: long-term safety and efficacy results. Aesthetic Surg J. 2010;30:235-238
8. Berlin AL, Hussain M, Goldberg DJ. Calcium hydroxylapatite filler for facial rejuvenation: a histologic and immunohistochemical analysis. Dermatol Surg. 2008;34:S64-S67.
9. Tsvi Segal, MD, Ana Schwartz, MD, Konstantin Konfino, MD, PhD: “Post Marketing Study of Safety and Efficacy of Crystalys, a Calcium
Hydroxylapatite Based Filler for Facial Soft Tissue Augmentation” , http://www.luminera.com
Note: These studies were done with CaHA technology based dermal fillers which are relevant since RENÚ® is a substantially equivalent product and contain the same components in equivalent formulations.